Yale (7-2) scored 25 points off of 17 turnovers by Bryant (1-8), with 11 of those coming on steals. Yale tallied 15 assists, and turned it over just 10 times.
Yale outscored Bryant 24-19 off the bench, and 49-32 in the second half. Mangano scored 15 points and grabbed seven rebounds after halftime.
Austin Morgan and Brandon Sherrod added 10 points each for Yale, which outscored Bryant 24-19 off the bench.
Bryant outshot Yale 47.9 percent (23 of 48) to 45.1 percent (23 of 51) from the field, but struggled from the free-throw line. Bryant was just 6 of 13 (46.2), while Yale made 82.1 percent from the foul line (23 of 28).
Corey Maynard paced Bryant with 15 points. Alex Francis and Claybrin McMath scored 10 points each for Bryant, which lost its seventh straight.