| Rank | Name | Pos | Location | Stars | Ht | Wt | School |
|---|---|---|---|---|---|---|---|
| #1 | Michael Hill | DT | Pendleton, SCPendleton Hill’s senior season ended early after tearing a ligament in his hand. He played eight games, where he finished with eight tackles for a loss and four sacks | 4 stars | 6'3" | 315 | Ohio St. |
| #2 | Ben Boulware | LB | Anderson, SCT. L. Hanna Finished the regular season with 180 tackles and four sacks. | 4 stars | 6'0" | 225 | Clemson |
| #3 | D.J. Park | OL | Dillon, SCDillon Started at left tackle for state champion Dillon. | 4 stars | 6'6" | 335 | South Carolina |
| #4 | Mike Williams | WR | Santee, SCLake Marion As a senior, Williams had 54 receptions for 1,395 yards and ten touchdowns. Defensively he also added 15 tackles and three interceptions. | 4 stars | 6'4" | 185 | Clemson |
| #5 | Tramel Terry | ATH | Goose Creek, SCGoose Creek Terry had 1,861 all- purpose yards his senior season and scored 24 touchdowns | 4 stars | 6'0" | 190 | Georgia |
| #6 | Bryce King | OL | Dillon, SCDillon Started on the offensive line for state champion Dillon. | 3 stars | 6'4" | 300 | South Carolina |
| #7 | Jadar Johnson | ATH | Orangeburg, SCOrangeburg Wilkinson Finished his senior season with eight interceptions and three forced fumbles. | 3 stars | 6'1" | 180 | Clemson |
| #8 | Gerald Turner | LB | Goose Creek, SCGoose Creek Finished his senior season with 49 tackles and eight sacks. | 3 stars | 6'1" | 256 | South Carolina |
| #9 | Jabo Lee | RB | Dillon, SCDillon Missed most of his senior season with nagging injuries. | 3 stars | 5'10" | 180 | Tennessee |
| #10 | Chocolate Wilson | DB | Myrtle Beach, SCMyrtle Beach Missed the entire regular season with a knee injury but returned for the playoffs and had 15 tackles. | 3 stars | 5'9" | 160 | Marshall |
| #11 | Marcus Edmond | ATH | Hopkins, SCLower Richland Rushed for 778 yards and six scores while throwing for 979 yards and 12 touchdowns. Had 33 tackles, three interceptions and four pass break-ups as a defensive back. | 3 stars | 6'1" | 175 | Clemson |
| #12 | Jaylen Miller | DE | Gaffney, SCGaffney Miller finished the year with 24.5 sacks and 62 tackles. | 3 stars | 6'3" | 265 | Tennessee |
| #13 | Mykal Moody | ATH | Conway, SCConway Threw for 1,600 yards, ran for 867 yards and scored 36 touchdowns while playing quarterback as a senior. | 3 stars | 5'11" | 180 | list |
| #14 | Harold Atkinson | RB | Myrtle Beach, SCCarolina Forest Finished his senior season with 941 yards rushing and nine touchdowns. | 3 stars | 6'1" | 210 | S. Carolina St. |
| #15 | Jalen Stevens | DE | Goose Creek, SCGoose Creek Finished his senior season with a 126 tackles and six sacks. | 3 stars | 6'4" | 218 | Connecticut |
| #16 | Justin Evans | OL | Florence, SCWilson Started at left tackle his junior and senior seasons at Wilson. | 3 stars | 6'6" | 275 | S. Carolina St. |
| #17 | Devaris Brunson | LB | Lake City, SCLake City Had 88 tackles, four sacks and two interceptions as a senior. | 3 stars | 6'0" | 206 | East Carolina |
| #18 | Justin Day | OL | Aiken, SCSouth Aiken Started at left tackle for South Aiken as a senior. | 3 stars | 6'8" | 285 | Kentucky |
| #19 | Gabe Brandner | OL | Columbia, SCHeathwood Hall Episcopal Started at left tackle for Heathwood Hall Episcopal as a senior. | 3 stars | 6'4" | 250 | Duke |
| #20 | Taylor Chambers | OL | Irmo, SCIrmo Started every game as a senior in only his third year of playing competitive football. | 3 stars | 6'7" | 285 | Wake Forest |